What happens at or after transcription: Insights into circRNA biogenesis and function
C Huang, G Shan - Transcription, 2015 - Taylor & Francis
C Huang, G Shan
Transcription, 2015•Taylor & FrancisCircular RNAs (circRNAs) are a large family of noncoding RNAs (ncRNAs) found in
metazoans. Systematic studies of circRNAs have just begun. Here, we discuss circRNA
biogenesis and functions with a focus on studies indicating great diversification of circRNAs.
We highlight the recent identification of a special subtype of circRNAs, called EIciRNAs, and
their role in transcriptional regulation. New insights on RNA-RNA interaction and other
features associated with circRNA biology are also discussed.
metazoans. Systematic studies of circRNAs have just begun. Here, we discuss circRNA
biogenesis and functions with a focus on studies indicating great diversification of circRNAs.
We highlight the recent identification of a special subtype of circRNAs, called EIciRNAs, and
their role in transcriptional regulation. New insights on RNA-RNA interaction and other
features associated with circRNA biology are also discussed.
Circular RNAs (circRNAs) are a large family of noncoding RNAs (ncRNAs) found in metazoans. Systematic studies of circRNAs have just begun. Here, we discuss circRNA biogenesis and functions with a focus on studies indicating great diversification of circRNAs. We highlight the recent identification of a special subtype of circRNAs, called EIciRNAs, and their role in transcriptional regulation. New insights on RNA-RNA interaction and other features associated with circRNA biology are also discussed.
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